Shëndeti në radhë të parë

Acid Urik (Uricemia)

Uric acid

Uric acid is a product of the exchange of purine nucleosides, which are part of nucleic acids (RNA and DNA). In this case, uric acid can be formed from foods coming from food, and as a result of the breakdown of the body's own nucleic acids. From the liver uric acid is transported by plasma to the kidneys, where approximately 70% is filtered and released. The remaining amount of uric acid is excreted through the gastrointestinal tract. Food purines under the influence of digestive enzymes break down to uric acid already in? the gastrointestinalpath, and then absorbed into the bloodstream. Formed uric acid is secreted by the kidneys. In blood plasma uric acid is in the form of a salt - sodium urate. This salt has a low solubility, and at a concentration just above the norm, urate crystals form. Overproduction of uric acid occurs in the following situations: excessive catabolism of nucleic acids, massive production and destruction of cells or inability to excrete the final product. Although hyperuricemia and hypo-uricemia are not an independent disease, hyperuricemia is a risk factor for the development of metabolic disorders and may underlie some diseases, and hypo-uricemia may indicate a latent pathological condition. The level of uric acid in the blood is labile and is associated with factors such as age, sex, alcohol consumption